The entourage effect is a term used to describe the synergistic interaction between various compounds found in cannabis, including cannabinoids, terpenes, and other plant compounds. This interaction is believed to enhance the overall effects of cannabis by working together to produce a more complex and nuanced effect than any one compound could produce on its own. In a study Dr. Ethan Russo a famous cannabis neurologist discusses the entourage effect and many of the more popularized cannabinoids.

The theory behind the entourage effect is that the various compounds in cannabis work together to modulate the effects of each other. For example, some terpenes may enhance the effects of certain cannabinoids, while other compounds may help to mitigate the less desirable effects of THC. This synergistic interaction is believed to contribute to the unique effects and therapeutic potential of cannabis.

Some research has suggested that the entourage effect may be responsible for some of the therapeutic benefits of cannabis, such as its ability to reduce inflammation, relieve pain, and improve mood. The best cannabis product to experience the entourage effect is flower or the bud of the cannabis plant. This is the most unadulterated form available.